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Hemolytic Anemia Causes, Symptoms, and Diagnosis?

venikrishna
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venikrishna
13:37, ուրբաթ, 02 դեկտեմբերի, 2022 թ.
Hemolytic Anemia Causes, Symptoms, and Diagnosis?

Destruction of red blood cells When the bone marrow overproduces these cells, hemolytic anemia occurs. Hemolytic anemia can be external or internal.

External hemolytic:

External hemolytic anemia develops when the spleen absorbs and destroys healthy red blood cells or by a number of mechanisms, such as the onset of an autoimmune reaction. It can also come from the destruction of red blood cells.

  • Infection:
  • Tumors:
  • Autoimmune disorders:
  • side effects of medications
  • Leukemia
  • Lymphoma

Internal hemolytic:

Internal hemolytic anemia develops when the red blood cells your body makes do not work properly. This condition is often inherited in people with sickle cell anemia or thalassemia with abnormal hemoglobin.

At other times, inherited metabolic abnormalities, such as red blood cell membrane instability, such as those with G6PD deficiency or inherited spherocytosis, can lead to this condition.

Causes:

The doctor may not be able to identify the source of the hemolytic anemia. However, many diseases and even some medications can cause this condition.

Causes of external hemolytic anemia.

  • Enlarged spleen
  • Infectious hepatitis
  • Epstein-Barr virus
  • Typhoid fever
  • E. coli toxin
  • Leukemia
  • Lymphoma
  • Tumors:

The systemic lupus erythematosus (SLE), an autoimmune disorder

Viscott-Aldrich syndrome, an autoimmune disorder

Symptoms:

The symptoms of hemolytic anemia are similar to the usual signs of anemia. Common signs and symptoms include fatigue, paleness, shortness of breath, and rapid heartbeat. In young children, it may happen that not any form of anemia develops. Also, symptoms of hemolysis can include chills, jaundice, dark urine, and an enlarged spleen. History Certain factors in the medical history, such as medications, drug side effects, autoimmune disorders, reactions to blood transfusions, presence of a prosthetic heart valve, or other medical conditions, may indicate a cause of hemolysis.

Risk factors:

Aplastic anemia is very rare. Risk factors:

Cancer treatment with radiation or high-dose chemotherapy

Exposure to toxic chemicals

Use of some prescription drugs. chloramphenicol and gold compounds used to treat bacterial infections and rheumatoid arthritis. Certain blood diseases, autoimmune disorders, and serious infections. Pregnancy, Sacramento.

Diagnosis:

Several tests are needed to diagnose hemolytic anemia. These tests can help diagnose, find the cause, and determine the severity of the condition.

Complete blood count

Often the primary test to diagnose anemia may be a complete blood count (CBC) . The CBC measures most of your blood.

This test checks your hemoglobin and hematocrit (she-mat-oh-cry) levels. Hemoglobin may be a high iron protein in red blood cells, which carries oxygen to the body. Hematocrit may be a measure of what proportion of space red blood cells take up in your blood. Low hemoglobin or hematocrit levels are a symbol of anemia.

Treatment:

Treatment options for hemolytic anemia vary depending on the cause of the anemia, the severity of the condition, your age, your health, and your tolerance for certain toxins.

Treatment options for hemolytic anemia.

  • Red blood cell transplant
  • IVIG:
  • Source of immunity booster such as corticosteroids
  • Surgery:
  • Red blood cell transplant
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